Genomic expression differences between cutaneous cells from red hair color individuals and black hair color individuals based on bioinformatic analysis
نویسندگان
چکیده
منابع مشابه
Genomic expression differences between cutaneous cells from red hair color individuals and black hair color individuals based on bioinformatic analysis
The MC1R gene plays a crucial role in pigmentation synthesis. Loss-of-function MC1R variants, which impair protein function, are associated with red hair color (RHC) phenotype and increased skin cancer risk. Cultured cutaneous cells bearing loss-of-function MC1R variants show a distinct gene expression profile compared to wild-type MC1R cultured cutaneous cells. We analysed the gene signature a...
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2016
ISSN: 1949-2553
DOI: 10.18632/oncotarget.14140